Nurse Practitioner Hourly Pay in Greenville, SC: $59.33 (2026)
Quick Answer:Hourly pay for a nurse practitioner working in Greenville, SC runs $59.33 at the median for 2026 — annualizing to $123,395 at a standard 2,080-hour year. Figures projected from BLS OEWS 2025 (SOC 29-1171). Weighted against Greenville's regional price level (BEA RPP 93.3, 7% below national), each hour of work buys what $63.62 nationally would. A 24-hour part-time schedule grosses $74,042 per year.
Official BLS data · View source

The nurse practitioner hourly pay in Greenville, SC, is projected to be $59.33 in 2026, which is notably lower than the national average of $65.80 per hour. This pay level translates to various opportunities for part-time and per-diem roles commonly found in diverse healthcare settings, including primary care exam rooms, hospital outpatient clinics, and urgent care facilities. With an hourly range starting at $40.74 for entry-level positions and advancing to $72.39 for the top earners, the financial prospects for nurse practitioners here can vary significantly based on experience, specialty, and the specific type of healthcare facility. These numbers are based on 2025 BLS OEWS data, projected to 2026, providing a reliable framework for understanding compensation in this field.
Nurse Practitioner Hourly Wage Breakdown
| Percentile | Hourly Rate | Per 8hr Shift |
|---|---|---|
| Entry Level (P10) | $40.74 | $325.91 |
| Lower Range (P25) | $54.73 | $437.80 |
| Median (P50) | $59.33 | $474.63 |
| Upper Range (P75) | $64.60 | $516.84 |
| Top Earners (P90) | $72.39 | $579.15 |
Estimated Annual Income by Work Schedule in Greenville
Based on $59.33/hr median hourly rate · 2026 est.
At $59.33/hr, a nurse practitioner working full-time (40 hr/wk) in Greenville, SC can expect to earn approximately $123,403 per year (2026 est.). Part-time hygienists working 24 hours per week would earn around $71,194. With a cost-of-living index of 93.26 (below the national average), these earnings stretch further in Greenville.
Hourly Rate Calculator
Schedule Comparison in Greenville
| Schedule | Weekly | Monthly | Annual |
|---|---|---|---|
| Full-Time (40 hrs) | $2,373.14 | $10,284 | $123,403 |
| Part-Time (24 hrs) | $1,423.89 | $6,170 | $74,042 |
| Per Diem (16 hrs) | $949.26 | $4,113 | $49,361 |
Compare NP Wages With Similar Roles
| Role | Median Hourly |
|---|---|
| Nurse Practitioner (Greenville) | $59.33 |
| Registered Nurse (National Avg) | $42.80 |
| Physician Assistant (National Avg) | $63.20 |
| Nurse Anesthetist (National Avg) | $103.40 |
| Nurse Midwife (National Avg) | $63.85 |
Nurse Practitioners in Greenville, SC earn a median of $123,395 per year (2026 est.), which is 9.84% lower than the national median of $136,864 and 0.80% below the South Carolina state average of $124,390.
Nurse Practitioner Hourly Pay vs. Cost of Living
Working 24h/week at $59.33/hr = $74,042/year (purchasing power: $79,393).
Working 40h/week (full-time) = $123,403/year (purchasing power: $132,322).
CoL index: 93.26 (100 = national average). Your dollars stretch further here.
2019 BLS Actual
$45.64/hr
2025 BLS Actual
$57.35/hr
2026 Current Est.
$59.33/hr
2019–2027 Growth
+34.5%
Hourly Rate Trajectory for Nurse Practitioners in Greenville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Hourly Rate | Status |
|---|---|---|
| 2019 | $45.64/hr | Actual |
| 2020 | $46.98/hr | Actual |
| 2021 | $48.50/hr | Actual |
| 2022 | $49.63/hr | Actual |
| 2023 | $52.71/hr | Actual |
| 2024 | $53.15/hr | Actual |
| 2025 | $57.35/hr | Actual |
| 2026(current) | $59.33/hr | Estimated |
| 2027 | $61.38/hr | Projected |
Based on 7 years of BLS OEWS metropolitan area data, the median hourly rate for nurse practitioners in Greenville grew 25.7% from $45.64/hr (2019) to $57.35/hr (2025). At a 3.45% projected growth rate, hourly pay is expected to reach $61.38/hr by 2027. Part-time and per-diem nurse practitioners can use this multi-year trend to benchmark future contract negotiations.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Greenville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Working as an Hourly Nurse Practitioner in Greenville
In considering the financial nuances of a nurse practitioner's career in Greenville, a part-time (3 days a week) NP working approximately 24 hours may have a different financial landscape compared to their full-time counterparts. While full-time positions offer stability, working part-time can yield decent income; however, the absence of benefits may also weigh heavily in decision-making. For those attracted to the flexibility of per-diem roles, pay rates can vary widely; locum tenens nurse practitioners may bill anywhere from $80 to $140 per hour depending on their specialty, while telehealth platforms may facilitate even higher rates for psychiatric mental health NPs, often earning $150 to $200 per hour. Furthermore, working in various healthcare settings—such as hospital outpatient clinics or retail health clinics—can lead to different compensation models. Often, NPs must weigh a lower hourly rate with benefits against a higher rate without them. Nurse practitioners in Greenville should negotiate effectively by understanding their worth in relation to the specific employer type, ensuring they secure the best possible working conditions and compensation.
More salary data for Greenville, SC:
Frequently Asked Questions
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Hourly wage figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. A 3.45% compound annual growth rate (CAGR), derived from 6-year national BLS wage trends, was applied to estimate current 2026 hourly rates for nurse practitioners in Greenville. Part-time and full-time income estimates assume consistent weekly hours and do not account for overtime, benefits, or seasonal variation.
Data Sources & Methodology
Source: BLS, OEWS, 7-year dataset (–). Per-city data from annual BLS metropolitan area surveys.
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov