Nurse Practitioner Salary in Clemson, SC: $114,507 (2026)
Quick Answer:A full-time nurse practitioner in Clemson, SC earns a median $114,507/year (≈ $55.06/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1171). Once you factor in Clemson's price level (8% below national, BEA RPP 91.5), that paycheck buys what $125,144 would nationally. Nominal pay sits 7.9% below the South Carolina state average.
Based on BLS state-level estimates · View source

In 2026, the nurse practitioner salary in Clemson, South Carolina, is projected to reach a median annual income of $114,507. This figure is notably lower than the national median of $136,864, reflecting a regional salary landscape that ranges from $94,159 at the 10th percentile to $144,324 at the 90th percentile. These estimates derived from BLS state-level data and regional price adjustments highlight the influence of the local market's full-practice authority status—a crucial factor for nurse practitioners who operate independently versus those required to maintain a collaborative agreement. As the demand for healthcare continues to rise, understanding the compensation dynamics specific to Clemson will be essential for both new graduates and seasoned professionals navigating this job market.
About the Clemson Market
Salary estimated from South Carolina average ($115,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $94,159 | $45.27 |
| Lower Range (P25) | $105,427 | $50.69 |
| Median (P50)(typical) | $114,507 | $55.06 |
| Upper Range (P75) | $133,482 | $64.17 |
| Top Earners (P90) | $144,324 | $69.38 |
Median Salary Position
16.34% below the national average
2026 Salary Percentile Distribution in Clemson
In Clemson, SC, the nurse practitioner salary spread from the 10th to 90th percentile is $50,165 (2026 est.). At $114,507, the local median is 16.34% below the national median of $136,864.
Salary Calculator
At 40 hours/week in Clemson: You'd be in the lower-middle range
How Clemson Nurse Practitioner Pay Compares
Clemson median: $114,507/year (2026)
| Compared To | Median Salary | Clemson Pays |
|---|---|---|
| South Carolina Average | $124,329 | -7.90% less |
| National Average | $136,864 | -16.34% less |
Nurse Practitioners in Clemson, SC earn a median of $114,507 per year (2026 est.), which is 16.34% lower than the national median of $136,864 and 7.90% below the South Carolina state average of $124,329.
Cost-of-Living Adjusted Salary
Clemson has a cost of living 8.50% below the national average, meaning your salary goes further here.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Clemson, SC has a cost-of-living index of 91.5 (below the national average of 100). A nurse practitioner earning $114,507 nominally has purchasing power equivalent to $125,144 in an average-cost city — an effective 9.29% boost.
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2019 BLS Actual
$91,880
2025 BLS Actual
$110,688
2026 Current Est.
$114,507
2019–2027 Growth
+28.9%
Salary Trajectory for Nurse Practitioners in Clemson (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.45% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $91,880 | Actual |
| 2020 | $93,436 | Actual |
| 2021 | $100,966 | Actual |
| 2022 | $101,744 | Actual |
| 2023 | $105,635 | Actual |
| 2024 | $96,898 | Actual |
| 2025 | $110,688 | Actual |
| 2026(current) | $114,507 | Estimated |
| 2027 | $118,457 | Projected |
Based on 7 years of BLS OEWS data for the Clemson metropolitan area, the median nurse practitioner salary grew 20.5% from $91,880 (2019) to $110,688 (2025). At a 3.45% compound annual growth rate, salaries are projected to reach $118,457 by 2027 — a total increase of $26,577 (28.93%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Clemson metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.45% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $94,159 – $105,427 |
| 3-5 years (Mid Career) | $105,427 – $114,507 |
| 5+ years (Experienced) | $114,507 – $133,482 |
| 10+ years (Top Earner) | $133,482 – $144,324 |
NP salary ranges estimated from BLS percentile data. Individual nurse practitioner compensation varies by employer, certifications, and specialization.
Nurse Practitioner Job Market in Clemson
The job market for nurse practitioners in Clemson is relatively concentrated, with only six practitioners currently employed in the area. The cost of living index stands at 91.5, indicating that residents enjoy a slightly lower cost of living compared to the national average, which can enhance purchasing power despite lower salary figures. Opportunities for higher compensation can arise from various employers, including hospital outpatient clinics and specialty clinics, where the potential for productivity bonuses and the focus on in-demand specialties can markedly affect overall earnings. Additionally, pursuing full-practice authority further opens avenues for increased autonomy and income potential, differing significantly across certifications, especially for PMHNPs facing the highest demand in the mental health sector. A strategic approach for optimizing salary in Clemson SC involves enhancing skill sets related to high-demand specialties and considering positions that offer lucrative bonus structures or engage in telehealth opportunities to supplement income.
More salary data for Clemson, SC:
Frequently Asked Questions
How much do nurse practitioners make in Clemson, SC in 2026?
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Can nurse practitioners make $100K in Clemson?
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Related Pages
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Written by Maria Gonzalez, MSN, NP-C
Career Analyst
Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $110,688 for nurse practitionersin the Clemson metropolitan area. A 3.45% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Clemson is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.45%, derived from historical BLS wage trends for nurse practitioners (SOC 29-1171).
Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov