Nurse Practitioner Pay

St. Louis vs University City: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between St. Louis, MO and University City, MO. All figures are 2026 estimates projected from BLS 2025 data.

St. Louis, MO
$136,120
$65.44/hr
University City, MO
$131,382
$63.17/hr

Side-by-Side Comparison

MetricSt. Louis, MOUniversity City, MO
Median Salary$136,120$131,382
Hourly Rate$65.44$63.17
Entry Level (P10)$112,078$102,232
25th Percentile$131,857$116,952
75th Percentile$159,830$153,564
Top Earner (P90)$169,948$162,436
Total Employed3,4306
Side-by-side bar chart comparing St. Louis ($136,120) and University City ($131,382) nurse practitioner salaries.St. LouisUniversity CityMedian Salary$136,120$131,382Entry Level (P10)$112,078$102,232Top Earner (P90)$169,948$162,436US Median $136,864

Verdict

St. Louis, MO offers better overall compensation for nurse practitioners, winning 4 out of 4 metrics compared to University City.

The salary gap between St. Louis and University City is $4,738 (3.61%). St. Louis's median is -0.54% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in St. Louis spans $57,870,University City spans $60,204. University City has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse practitioners.

St. Louis
P10 (Entry)$112,078
P25$131,857
Median$136,120
P75$159,830
P90 (Top)$169,948
University City
P10 (Entry)$102,232
P25$116,952
Median$131,382
P75$153,564
P90 (Top)$162,436

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, University City ($146,632 effective) pays 2.43% more than St. Louis ($143,152 effective).

St. Louis
Nominal: $136,120
CoL Index: 95.088
Adjusted: $143,152
University City
Nominal: $131,382
CoL Index: 89.6
Adjusted: $146,632

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose St. Louis if…

  • Higher median salary ($136,120/year)
  • Better top-earner potential ($169,948)
  • Larger job market (3,430 employed)
  • You prefer the Missouri area and lifestyle

Choose University City if…

  • Better purchasing power (CoL-adjusted: $146,632)
  • You prefer the Missouri area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in St. Louis grew 31.1% from 2019 to 2025, compared to 22.9% growth in University City over the same period.

St. Louis, MO

+31.1%

$100,340 (2019) → $131,580 (2025)

University City, MO

+22.9%

$103,351 (2024) → $127,000 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: St. Louis or University City?

St. Louis has a higher median nurse practitioner salary at $136,120/year, compared to University City at $131,382/year — a difference of $4,738 (3.61%).

What is the hourly rate difference between St. Louis and University City?

St. Louis nurse practitioners earn $65.44/hr while University City hygienists earn $63.17/hr (2026 est.).

Should I relocate from St. Louis to University City as a nurse practitioner?

Consider more than just salary when comparing St. Louis and University City. Factor in cost of living (CoL-adjusted: St. Louis = $143,152, University City = $146,632), job availability (3,430 vs 6 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in St. Louis vs University City?

Entry-level (10th percentile) nurse practitioners earn $112,078 in St. Louis and $102,232 in University City. The St. Louis area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov