Nurse Practitioner Pay

Houston vs San Angelo: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between Houston, TX and San Angelo, TX. All figures are 2026 estimates projected from BLS 2025 data.

Houston, TX
$139,202
$66.92/hr
San Angelo, TX
$133,637
$64.25/hr

Side-by-Side Comparison

MetricHouston, TXSan Angelo, TX
Median Salary$139,202$133,637
Hourly Rate$66.92$64.25
Entry Level (P10)$100,222$105,902
25th Percentile$120,519$129,178
75th Percentile$148,637$139,854
Top Earner (P90)$164,310$164,992
Total Employed5,970200
Side-by-side bar chart comparing Houston ($139,202) and San Angelo ($133,637) nurse practitioner salaries.HoustonSan AngeloMedian Salary$139,202$133,637Entry Level (P10)$100,222$105,902Top Earner (P90)$164,310$164,992US Median $136,864

Verdict

Houston, TX offers better overall compensation for nurse practitioners, winning 3 out of 4 metrics compared to San Angelo.

The salary gap between Houston and San Angelo is $5,565 (4.16%). Houston's median is +1.71% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Houston spans $64,088,San Angelo spans $59,090. Houston has a wider pay range, meaning more potential for high earners but also more variation.

Houston
P10 (Entry)$100,222
P25$120,519
Median$139,202
P75$148,637
P90 (Top)$164,310
San Angelo
P10 (Entry)$105,902
P25$129,178
Median$133,637
P75$139,854
P90 (Top)$164,992

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Angelo ($144,546 effective) pays 2.42% more than Houston ($141,137 effective).

Houston
Nominal: $139,202
CoL Index: 98.629
Adjusted: $141,137
San Angelo
Nominal: $133,637
CoL Index: 92.453
Adjusted: $144,546

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Houston if…

  • Higher median salary ($139,202/year)
  • Larger job market (5,970 employed)
  • You prefer the Texas area and lifestyle

Choose San Angelo if…

  • Better top-earner potential ($164,992)
  • Better purchasing power (CoL-adjusted: $144,546)
  • You prefer the Texas area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in Houston grew 12.8% from 2019 to 2025, compared to 18.2% growth in San Angelo over the same period.

Houston, TX

+12.8%

$119,290 (2019) → $134,560 (2025)

San Angelo, TX

+18.2%

$109,320 (2019) → $129,180 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: Houston or San Angelo?

Houston has a higher median nurse practitioner salary at $139,202/year, compared to San Angelo at $133,637/year — a difference of $5,565 (4.16%).

What is the hourly rate difference between Houston and San Angelo?

Houston nurse practitioners earn $66.92/hr while San Angelo hygienists earn $64.25/hr (2026 est.).

Should I relocate from Houston to San Angelo as a nurse practitioner?

Consider more than just salary when comparing Houston and San Angelo. Factor in cost of living (CoL-adjusted: Houston = $141,137, San Angelo = $144,546), job availability (5,970 vs 200 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in Houston vs San Angelo?

Entry-level (10th percentile) nurse practitioners earn $100,222 in Houston and $105,902 in San Angelo. The San Angelo area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov