Nurse Practitioner Pay

Costa Mesa vs San Francisco: Nurse Practitioner Salary (2026)

Compare nurse practitioner salaries between Costa Mesa, CA and San Francisco, CA. All figures are 2026 estimates projected from BLS 2025 data.

Costa Mesa, CA
$172,643
$83.00/hr
San Francisco, CA
$226,638
$108.96/hr

Side-by-Side Comparison

MetricCosta Mesa, CASan Francisco, CA
Median Salary$172,643$226,638
Hourly Rate$83.00$108.96
Entry Level (P10)$130,700$158,568
25th Percentile$151,968$182,579
75th Percentile$209,003$250,256
Top Earner (P90)$235,047$283,412
Total Employed233,110
Side-by-side bar chart comparing Costa Mesa ($172,643) and San Francisco ($226,638) nurse practitioner salaries.Costa MesaSan FranciscoMedian Salary$172,643$226,638Entry Level (P10)$130,700$158,568Top Earner (P90)$235,047$283,412US Median $136,864

Verdict

San Francisco, CA offers better overall compensation for nurse practitioners, winning 4 out of 4 metrics compared to Costa Mesa.

The salary gap between Costa Mesa and San Francisco is $53,995 (31.28%). San Francisco's median is +65.59% compared to the US national median of $136,864.

Salary Range Comparison

The full salary range (10th to 90th percentile) in Costa Mesa spans $104,347,San Francisco spans $124,844. San Francisco has a wider pay range, suggesting more variation in pay between entry-level and experienced nurse practitioners.

Costa Mesa
P10 (Entry)$130,700
P25$151,968
Median$172,643
P75$209,003
P90 (Top)$235,047
San Francisco
P10 (Entry)$158,568
P25$182,579
Median$226,638
P75$250,256
P90 (Top)$283,412

Cost-of-Living Adjusted Comparison

After cost-of-living adjustment, San Francisco ($196,032 effective) pays 28.42% more than Costa Mesa ($152,646 effective).

Costa Mesa
Nominal: $172,643
CoL Index: 113.1
Adjusted: $152,646
San Francisco
Nominal: $226,638
CoL Index: 115.613
Adjusted: $196,032

Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.

Which City Is Right for You?

Choose Costa Mesa if…

  • You prefer the California area and lifestyle

Choose San Francisco if…

  • Higher median salary ($226,638/year)
  • Better top-earner potential ($283,412)
  • Larger job market (3,110 employed)
  • Better purchasing power (CoL-adjusted: $196,032)
  • You prefer the California area and lifestyle

Historical Salary Growth Comparison

Based on BLS OEWS metropolitan area data, nurse practitioner salaries in Costa Mesa grew -10.5% from 2024 to 2025, compared to 58.6% growth in San Francisco over the same period.

Costa Mesa, CA

+-10.5%

$186,372 (2024) → $166,885 (2025)

San Francisco, CA

+58.6%

$138,100 (2019) → $219,080 (2025)

View Full Salary Data

Frequently Asked Questions

Which city pays nurse practitioners more: Costa Mesa or San Francisco?

San Francisco has a higher median nurse practitioner salary at $226,638/year, compared to Costa Mesa at $172,643/year — a difference of $53,995 (31.28%).

What is the hourly rate difference between Costa Mesa and San Francisco?

Costa Mesa nurse practitioners earn $83.00/hr while San Francisco hygienists earn $108.96/hr (2026 est.).

Should I relocate from Costa Mesa to San Francisco as a nurse practitioner?

Consider more than just salary when comparing Costa Mesa and San Francisco. Factor in cost of living (CoL-adjusted: Costa Mesa = $152,646, San Francisco = $196,032), job availability (23 vs 3,110 employed), commute, and career growth potential.

What do entry-level nurse practitioners earn in Costa Mesa vs San Francisco?

Entry-level (10th percentile) nurse practitioners earn $130,700 in Costa Mesa and $158,568 in San Francisco. The San Francisco area offers higher starting salaries.

Related Comparisons

MG

Written by Maria Gonzalez, MSN, NP-C

Career Analyst

Maria has 10 years of experience in adult healthcare. She works in a community health clinic. Her specialty is chronic disease management.

Clinically reviewed by James Patel, DNP, APRNData verified by Aisha Khan, MSN, FNP-BC

Methodology & Data Source

All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.45% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.

Data Sources & Methodology

Source: BLS, OEWS , released .

Compiled and verified by Maria Gonzalez, MSN, NP-C, a licensed nurse practitioner with 10+ years of clinical experience. · View source data at BLS.gov